Salmon DNA microneedling is one of the most talked-about treatments to come out of Korean clinics, and for good reason: it takes classic microneedling and adds a repair-boosting ingredient that helps skin heal faster and hold more moisture. Here is what it is, how it works, and what makes it different from standard microneedling.
What salmon DNA (PDRN) actually is
PDRN is a polynucleotide derived from purified salmon DNA. It is a regenerative ingredient that helps skin cells repair themselves and hold on to water. On its own it is impressive, and delivered through the tiny micro-channels that needling creates, it goes exactly where it is needed.
How the treatment works
Microneedling uses fine needles to create controlled micro-channels in the skin. Your body treats these as something to repair, so it builds new collagen. Adding the PDRN serum on top means you get the collagen boost of needling plus faster recovery, deeper hydration and a plumper, more radiant finish than needling alone.
What it helps with
- Fine lines and early signs of ageing
- Dullness and dehydration
- Uneven texture and enlarged-looking pores
- Skin that has lost its bounce
- Overall glow and skin quality
What to expect
We numb the skin first, so most people find it very manageable. Afterwards your skin will be pink and warm, a little like mild sunburn, and it tends to settle faster than standard needling thanks to the PDRN. Many people see a glow after a single session, and a short course of three to four, spaced four to six weeks apart, gives the best result.
Standard microneedling or salmon DNA?
If your goal is a straightforward collagen boost, standard microneedling does the job. If you want faster recovery and a bigger hit of hydration and glow, salmon DNA is worth the upgrade. Our side-by-side comparison goes into more detail.
Salmon DNA microneedling is available at our Essendon North clinic. See the full details on our Salmon DNA microneedling page, or book a consultation.
Book a free skin consultation
Not sure which treatment is right for you? Our therapists will look at your skin and recommend the best option, plan or package for your goals.





